INT287925

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HNF4A) nucleoplasm (HNF4A) nucleus (HNF4A)
DNA binding (HNF4A) cytoplasm (HNF4A)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 14 92.24 High High
cINOD 26 5.00 Very Low Very Low Very Low
aspirin 14 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 162 99.60 Very High Very High Very High
Rheumatoid Arthritis 16 82.80 Quite High
Metastasis 8 77.08 Quite High
Carcinoma 4 72.44 Quite High
Adenoma 4 71.92 Quite High
Colon Cancer 20 58.64 Quite High
Apoptosis 36 57.76 Quite High
Disease 36 50.32 Quite High
Colorectal Cancer 36 5.00 Very Low Very Low Very Low
Familial Adenomatous Polyposis 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin/Tcf complex is thus an attractive target for anti-cancer drugs, but any such compound must selectively interfere with the complex without disrupting other essential interactions of ?
Regulation (target) of Tcf Binding (complex) of associated with cancer
1) Confidence 0.06 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.65 Pain Relevance 0
-catenin/Tcf complex is an enticing target for rational design of cancer therapeutics, but the promiscuity of ?
Regulation (target) of Tcf Binding (complex) of associated with cancer
2) Confidence 0.06 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.45 Pain Relevance 0.05

General Comments

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