INT287949

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CDH1) cell adhesion (CDH1) Golgi apparatus (CDH1)
plasma membrane (CDH1) cytoplasm (CDH1)
CDH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 28 5.00 Very Low Very Low Very Low
aspirin 21 5.00 Very Low Very Low Very Low
antagonist 18 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 10 94.80 High High
Carcinoma 5 86.76 High High
Cancer 175 86.32 High High
Apoptosis 39 85.52 High High
Repression 3 80.32 Quite High
Malignant Neoplastic Disease 5 66.12 Quite High
Leukemia 4 59.04 Quite High
Meningioma 2 56.08 Quite High
Colon Cancer 23 30.48 Quite Low
Metastasis 10 18.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MiR-200a targets the mRNA of the E-cadherin repressor proteins ZEB1(also known as Tcf8) and ZEB2 (also known as SIP1), subsequently increases the total E-cadherin available for binding to ?
Positive_regulation (increases) of Positive_regulation (available) of E-cadherin
1) Confidence 0.06 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.29 Pain Relevance 0
This is in agreement with data shown by Ohira et al who have shown induction of the Wnt signaling pathway target gene, E-cadherin, by HDAC inhibition with TSA or GSK3?
Positive_regulation (by) of Positive_regulation (induction) of E-cadherin
2) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.56 Pain Relevance 0
This is in agreement with data shown by Ohira et al who have shown induction of the Wnt signaling pathway target gene, E-cadherin, by HDAC inhibition with TSA or GSK3?
Positive_regulation (with) of Positive_regulation (induction) of E-cadherin
3) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.56 Pain Relevance 0

General Comments

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