INT288160

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd44) Golgi apparatus (Cd44) plasma membrane (Cd44)
nucleus (Cd44) protein complex (Cd44) cytoplasm (Cd44)
Anatomy Link Frequency
T cells 1
Cd44 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 3 68.24 Quite High
Multiple sclerosis 17 65.20 Quite High
Inflammation 10 48.00 Quite Low
dexamethasone 22 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 11 96.08 Very High Very High Very High
Multiple Sclerosis 50 92.16 High High
Apoptosis 37 86.00 High High
INFLAMMATION 15 67.84 Quite High
Death 13 5.00 Very Low Very Low Very Low
Central Nervous System Disease 6 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Paraparesis 3 5.00 Very Low Very Low Very Low
Immunization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The beneficial effect of CpdA required expression of the GR in T cells and was achieved by down regulating LFA-1 and CD44 on peripheral Th cells and by repressing IL-17 production.


Regulation (regulating) of CD44 in T cells
1) Confidence 0.42 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2781169 Disease Relevance 0.67 Pain Relevance 0.10

General Comments

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