INT288190

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Pik3r1) protein complex (Pik3r1) cytoplasm (Pik3r1)
cytosol (Pik3r1) signal transduction (Pik3r1) nucleus (Pik3r1)
Anatomy Link Frequency
proximal 2
Pik3r1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 38 84.48 Quite High
Inflammatory response 13 66.00 Quite High
Inflammation 27 50.00 Quite Low
tolerance 14 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 41 66.00 Quite High
Lyme Disease 13 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Susceptibility 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Mycobacterial Infection 1 5.00 Very Low Very Low Very Low
Myocarditis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that regulated localization of PI3K (and likely other molecules) to B. burgdorferi-induced lipid rafts links proximal membrane events to distal intracellular signaling cascades.


Regulation (regulated) of Localization (localization) of PI3K in proximal
1) Confidence 0.04 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2781632 Disease Relevance 0.07 Pain Relevance 0.10

General Comments

This test has worked.

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