INT288198

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr4, Mapk14) mitochondrion (Mapk14) cell morphogenesis (Mapk14)
intracellular (Tlr4) response to stress (Mapk14) cytosol (Mapk14)
Tlr4 (Mus musculus)
Mapk14 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 94.28 High High
cytokine 38 86.80 High High
Inflammation 27 86.44 High High
Inflammatory response 13 85.20 High High
tolerance 14 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 41 86.44 High High
Lyme Disease 13 70.84 Quite High
Disease 4 66.80 Quite High
Infection 4 42.96 Quite Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Susceptibility 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Mycobacterial Infection 1 5.00 Very Low Very Low Very Low
Myocarditis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This hyporesponsiveness has been attributed to the lower affinity of non-CD14-complexed LPS for TLR4 [7], the requirement for CD14 in MyD88-independent signaling [8], and/or the inability of p38, a member of the serine/threonine MAPK family, to be induced in the absence of CD14 [9].
LPS Binding (complexed) of p38
1) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2781632 Disease Relevance 0.63 Pain Relevance 0.31

General Comments

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