INT288201

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk14) cell morphogenesis (Mapk14) response to stress (Mapk14)
cytoplasm (Mapk14) cytosol (Mapk14) plasma membrane (Cish)
Mapk14 (Mus musculus)
Cish (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 28 97.68 Very High Very High Very High
cytokine 76 86.28 High High
Inflammation 54 64.40 Quite High
chemokine 4 58.08 Quite High
cINOD 2 7.28 Low Low
Inflammatory response 26 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 82 64.40 Quite High
Lyme Disease 26 34.64 Quite Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Infection 8 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Disease Susceptibility 4 5.00 Very Low Very Low Very Low
Bacterial Infection 4 5.00 Very Low Very Low Very Low
Mycobacterial Infection 2 5.00 Very Low Very Low Very Low
Myocarditis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
lacking CD14 which, in turn, results from impaired p38-mediated SOCS activity.
p38 Positive_regulation (mediated) of SOCS
1) Confidence 0.03 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2781632 Disease Relevance 0 Pain Relevance 0.39
Here we mechanistically link these previous findings by showing that CD14 recognition of B. burgdorferi triggers p38-dependent SOCS activity to impose a tolerant phenotype within M?.
p38 Positive_regulation (dependent) of SOCS
2) Confidence 0.03 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2781632 Disease Relevance 0.06 Pain Relevance 0.44

General Comments

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