INT288265

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (FLG) nucleus (NEUROG1) cytoplasmic membrane-bounded vesicle (FLG)
DNA binding (NEUROG1)
Anatomy Link Frequency
esophagus epithelium 1
FLG (Homo sapiens)
NEUROG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 60 97.26 Very High Very High Very High
Inflammation 2 65.48 Quite High
Fibrositis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 61 97.26 Very High Very High Very High
Autoimmune Disease 3 81.20 Quite High
Arthritis 1 65.48 Quite High
Disease 12 5.00 Very Low Very Low Very Low
Rheumatic Diseases 9 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 5 5.00 Very Low Very Low Very Low
Sleep Disorders 4 5.00 Very Low Very Low Very Low
Crystal Associated Disease 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among autoantibodies found in RA, the antiperinuclear factor (APF) that recognizes perinuclear granules in human buccal keratinocytes (4), and the antikeratin antibody (AKA) that recognizes water-soluble acidic-neutral isoforms of filaggrin in the human epidermis (5) and various molecular forms of (pro) filaggrin in the rat esophagus epithelium (6), were known to be the most specific antibodies in RA.
filaggrin Binding (recognizes) of AKA in esophagus epithelium associated with rheumatoid arthritis
1) Confidence 0.02 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782206 Disease Relevance 1.06 Pain Relevance 0.46

General Comments

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