INT288332

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.41
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 1
Sod1m (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 21 99.76 Very High Very High Very High
Inflammation 51 73.36 Quite High
Spinal cord 3 50.88 Quite High
Inflammatory response 24 49.92 Quite Low
chemokine 8 47.20 Quite Low
imagery 1 37.36 Quite Low
positron emission tomography 4 37.04 Quite Low
cytokine 34 33.04 Quite Low
Central nervous system 47 6.56 Low Low
agonist 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 97 99.76 Very High Very High Very High
Motor Neuron Diseases 33 97.84 Very High Very High Very High
Death 16 97.48 Very High Very High Very High
Targeted Disruption 19 91.68 High High
Disease 158 86.60 High High
Toxicity 7 82.28 Quite High
Neurodegenerative Disease 32 73.68 Quite High
Prion Diseases 13 68.52 Quite High
Alzheimer's Dementia 11 65.52 Quite High
Drug Induced Neurotoxicity 10 55.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, microglia with mSOD1 release more superoxide, nitrate and nitrite and induce more neuronal death [114].
Localization (release) of mSOD1 in neuronal associated with death
1) Confidence 0.04 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913815 Disease Relevance 1.26 Pain Relevance 0
Consistent with this idea, mSOD1 mice stimulated with LPS secrete more inflammatory mediators, including TNF [135], MCP-1, TGF-?
Localization (secrete) of mSOD1 associated with inflammatory mediators
2) Confidence 0.04 Published 2009 Journal Mol Neurodegener Section Body Doc Link PMC2784760 Disease Relevance 1.14 Pain Relevance 0.17

General Comments

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