INT288349

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (TNF, Mcpt1) intracellular (TNF, Mcpt1) peptidase activity (Mcpt1)
signal transduction (TNF) extracellular space (TNF) plasma membrane (TNF)
TNF (Homo sapiens)
Mcpt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 18 100.00 Very High Very High Very High
Inflammation 44 77.84 Quite High
Spinal cord 2 55.36 Quite High
chemokine 5 44.92 Quite Low
imagery 1 35.08 Quite Low
positron emission tomography 4 34.76 Quite Low
cytokine 25 30.76 Quite Low
Central nervous system 26 5.00 Very Low Very Low Very Low
Inflammatory response 17 5.00 Very Low Very Low Very Low
cINOD 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 83 99.98 Very High Very High Very High
Death 7 94.60 High High
Targeted Disruption 10 89.40 High High
Disease 103 88.48 High High
Motor Neuron Diseases 22 82.88 Quite High
Drug Induced Neurotoxicity 4 60.32 Quite High
Disease Progression 2 52.00 Quite High
Neurodegenerative Disease 15 50.00 Quite Low
Lifespan 1 30.48 Quite Low
Respiratory Failure 1 25.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this idea, mSOD1 mice stimulated with LPS secrete more inflammatory mediators, including TNF [135], MCP-1, TGF-?
TNF Positive_regulation (mediators) of Gene_expression ([135) of MCP-1 associated with inflammatory mediators
1) Confidence 0.02 Published 2009 Journal Mol Neurodegener Section Body Doc Link PMC2784760 Disease Relevance 1.10 Pain Relevance 0.18

General Comments

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