INT288354

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Context Info
Confidence 0.60
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Mgrn1) plasma membrane (Mgrn1) nucleus (Mgrn1)
ligase activity (Mgrn1) cytoplasm (Mgrn1)
Anatomy Link Frequency
melanocytes 1
Mgrn1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 8 96.48 Very High Very High Very High
antagonist 2 92.04 High High
melanocortin 1 receptor 58 90.64 High High
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Microphthalmia 4 27.24 Quite Low
Sprains And Strains 10 8.16 Low Low
Vibrio Infection 6 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice with null mutations at the attractin (Atrn, formerly mahogany) or mahogunin (Mgrn1, formerly mahoganoid) loci produce eumelanin and no pheomelanin, even in the presence of ASIP (He et al., 2001, 2003).
Neg (no) Gene_expression (produce) of Mgrn1
1) Confidence 0.60 Published 2009 Journal Pigment Cell & Melanoma Research Section Body Doc Link PMC2784899 Disease Relevance 0 Pain Relevance 0.53
Atrn and Mgrn1-null melanocytes: partial biological responses to ASIP but not ASIP-YY
Gene_expression (melanocytes) of Mgrn1-null in melanocytes
2) Confidence 0.60 Published 2009 Journal Pigment Cell & Melanoma Research Section Body Doc Link PMC2784899 Disease Relevance 0 Pain Relevance 0.05

General Comments

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