INT288383

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CHIT1) extracellular region (CHIT1) carbohydrate metabolic process (CHIT1)
lysosome (CHIT1)
CHIT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 9.84 Low Low
Inflammation 22 5.00 Very Low Very Low Very Low
cytokine 20 5.00 Very Low Very Low Very Low
Inflammatory stimuli 8 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 42 99.06 Very High Very High Very High
Lymphatic Filariasis 50 93.68 High High
Disease 12 92.92 High High
Lymphedema 98 87.36 High High
Filariasis 12 87.08 High High
Hydrocele 56 73.76 Quite High
Helminth Infection 50 16.00 Low Low
INFLAMMATION 36 9.48 Low Low
Death 12 5.00 Very Low Very Low Very Low
Fever 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Choi et al. have shown in a study in South India that patients are more susceptible to W. bancrofti infection if they are homozygous for the allele that is responsible for lower levels of chitotriosidase (CHIT1), a protein found in phagocytic cells (73).
Regulation (responsible) of Gene_expression (levels) of chitotriosidase associated with infection
1) Confidence 0.18 Published 2009 Journal Parasite Immunology Section Body Doc Link PMC2784903 Disease Relevance 1.50 Pain Relevance 0
Choi et al. have shown in a study in South India that patients are more susceptible to W. bancrofti infection if they are homozygous for the allele that is responsible for lower levels of chitotriosidase (CHIT1), a protein found in phagocytic cells (73).
Regulation (responsible) of Gene_expression (levels) of CHIT1 associated with infection
2) Confidence 0.14 Published 2009 Journal Parasite Immunology Section Body Doc Link PMC2784903 Disease Relevance 1.50 Pain Relevance 0

General Comments

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