INT288384

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.04
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CHIT1) extracellular region (CHIT1) carbohydrate metabolic process (CHIT1)
lysosome (CHIT1)
Anatomy Link Frequency
plasma 1
platelet 1
CHIT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 2 94.68 High High
Pain 11 89.48 High High
imagery 8 69.44 Quite High
Inflammatory response 2 5.16 Low Low
Inflammation 11 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 21 100.00 Very High Very High Very High
Gauchers Disease 60 96.12 Very High Very High Very High
Pain 8 89.48 High High
Lymphatic Filariasis 25 89.00 High High
Disease 24 88.24 High High
Compression Fractures 6 86.20 High High
Hydrocele 28 83.04 Quite High
Necrosis 18 82.92 Quite High
Lymphedema 49 82.68 Quite High
Filariasis 6 82.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chitotriosidase activity in plasma samples was determined using the fluorescent substrate 4-methyl umbeliferyl ?
Chitotriosidase Binding (activity) of in plasma
1) Confidence 0.15 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945057 Disease Relevance 0.50 Pain Relevance 0.22
Interestingly, no association of susceptibility to infection with CHIT1 was found in Papua New Guinea (74), demonstrating the importance of genotyping populations from different endemic areas.
CHIT1 Neg (no) Binding (association) of associated with infection
2) Confidence 0.14 Published 2009 Journal Parasite Immunology Section Body Doc Link PMC2784903 Disease Relevance 1.37 Pain Relevance 0
For patients given full-dose ERT, platelet counts increased slightly faster, ferritin and TRAP decreased faster, but chitotriosidase and ACE declined more slowly.
chitotriosidase Binding (declined) of in platelet
3) Confidence 0.13 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945057 Disease Relevance 0.18 Pain Relevance 0

General Comments

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