INT288491

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.85
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Tlr3) cytoplasm (Tlr3)
Anatomy Link Frequency
proximal 4
Tlr3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nud 12 96.00 Very High Very High Very High
spastic colon 68 72.12 Quite High
cytokine 30 66.00 Quite High
Inflammation 32 65.64 Quite High
Catecholamine 4 5.00 Very Low Very Low Very Low
noradrenaline 4 5.00 Very Low Very Low Very Low
abdominal pain 4 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
allodynia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 24 99.88 Very High Very High Very High
Genetic Predisposition To Disease 32 99.72 Very High Very High Very High
Dyspepsia 12 96.00 Very High Very High Very High
Stress 98 80.80 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

68 72.12 Quite High
INFLAMMATION 32 65.64 Quite High
Functional Bowel Disorder 8 44.44 Quite Low
Infection 14 5.00 Very Low Very Low Very Low
Abdominal Pain 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
WKY animals have increased mRNA expression of TLR3 in the proximal (p?
Positive_regulation (increased) of Transcription (expression) of TLR3 in proximal associated with genetic predisposition to disease
1) Confidence 0.37 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2785428 Disease Relevance 0.63 Pain Relevance 0.05
The WKY strain have increased levels of mRNA expression of TLR3, 4, 5, 7, 8, 9 & 10 in both the distal and proximal colonic mucosa compared to the control Sprague-Dawley strain.
Positive_regulation (increased) of Transcription (expression) of TLR3 in proximal associated with sprains and strains
2) Confidence 0.34 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2785428 Disease Relevance 1.15 Pain Relevance 0.14

General Comments

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