INT288497

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr7, Tlr9) endoplasmic reticulum (Tlr7, Tlr9) plasma membrane (Tlr7, Tlr9)
lysosome (Tlr7, Tlr9) cytoplasm (Tlr7, Tlr9) signal transduction (Tlr7)
Tlr7 (Rattus norvegicus)
Tlr9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 16 86.56 High High
cytokine 15 85.52 High High
spastic colon 34 78.88 Quite High
abdominal pain 2 76.16 Quite High
nud 6 51.00 Quite High
Catecholamine 2 5.00 Very Low Very Low Very Low
noradrenaline 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
allodynia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 49 94.72 High High
Sprains And Strains 12 93.64 High High
Genetic Predisposition To Disease 16 91.04 High High
INFLAMMATION 16 86.56 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

34 78.88 Quite High
Abdominal Pain 2 76.16 Quite High
Syndrome 1 58.08 Quite High
Anxiety Disorder 1 51.92 Quite High
Dyspepsia 6 51.00 Quite High
Functional Bowel Disorder 4 40.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TLR7 is known to bind to ssRNA from viruses [43] and TLR9 is known to bind to methylated DNA from bacteria and viruses [44] while there is no known ligand for TLR10 at present.
TLR7 Binding (bind) of TLR9
1) Confidence 0.21 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2785428 Disease Relevance 0.89 Pain Relevance 0.27

General Comments

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