INT288518

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gch1) nucleolus (Gch1) nucleus (Gch1)
protein complex assembly (Gch1) protein complex (Gch1) cytoplasm (Gch1)
Gch1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GCH1 56 100.00 Very High Very High Very High
Pain 46 99.56 Very High Very High Very High
dorsal root ganglion 16 91.28 High High
Stimulus evoked pain 1 57.08 Quite High
Dorsal horn 4 53.12 Quite High
Neuropathic pain 14 50.00 Quite Low
Serotonin 1 45.32 Quite Low
Tetrahydrobiopterin 4 41.76 Quite Low
Spinal cord 6 38.12 Quite Low
Inflammation 10 36.80 Quite Low
Disease Link Frequency Relevance Heat
Pain 52 99.56 Very High Very High Very High
Toxicity 1 97.16 Very High Very High Very High
Ganglion Cysts 16 91.28 High High
Neurodegenerative Disease 2 84.80 Quite High
Hypersensitivity 1 57.08 Quite High
Neuropathic Pain 17 50.00 Quite Low
Dystonia 1 47.68 Quite Low
Inborn Genetic Diseases 1 46.32 Quite Low
INFLAMMATION 10 36.80 Quite Low
Nervous System Injury 13 30.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our study, a single injection of the virus led to consistent down-regulation of GCH1 expression following pain surgery, and improved pain resistance over time.
Regulation (regulation) of Gene_expression (expression) of GCH1 associated with pain and gch1
1) Confidence 0.42 Published 2009 Journal Mol Pain Section Body Doc Link PMC2785765 Disease Relevance 0.91 Pain Relevance 0.88

General Comments

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