INT288520

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gch1) nucleolus (Gch1) nucleus (Gch1)
protein complex assembly (Gch1) protein complex (Gch1) cytoplasm (Gch1)
Gch1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
GCH1 56 100.00 Very High Very High Very High
Pain 46 99.48 Very High Very High Very High
Neuropathic pain 14 91.04 High High
Tetrahydrobiopterin 4 79.44 Quite High
tolerance 1 63.12 Quite High
Opioid 1 53.44 Quite High
cINOD 1 52.92 Quite High
allodynia 3 50.16 Quite High
Hyperalgesia 1 47.64 Quite Low
Spontaneous pain 1 45.44 Quite Low
Disease Link Frequency Relevance Heat
Pain 52 99.48 Very High Very High Very High
Neuropathic Pain 17 91.04 High High
Nervous System Injury 13 85.72 High High
Neurodegenerative Disease 2 51.28 Quite High
Hyperalgesia 1 47.64 Quite Low
INFLAMMATION 10 42.40 Quite Low
Chronic Disease 1 38.96 Quite Low
Ganglion Cysts 16 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, healthy individuals with the GCH1 haplotype experienced reduced GCH1 activation and lowered pain sensitivity.
Negative_regulation (reduced) of Positive_regulation (activation) of GCH1 associated with pain and gch1
1) Confidence 0.40 Published 2009 Journal Mol Pain Section Body Doc Link PMC2785765 Disease Relevance 0.67 Pain Relevance 1.02

General Comments

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