INT288537

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.92
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccr3, Ccl11) endosome (Ccr3) signal transduction (Ccr3)
extracellular region (Ccl11) plasma membrane (Ccr3) cytoskeleton organization (Ccl11)
Anatomy Link Frequency
eosinophils 2
Ccr3 (Mus musculus)
Ccl11 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 4 100.00 Very High Very High Very High
Inflammatory response 2 75.88 Quite High
tolerance 2 71.16 Quite High
cytokine 58 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
lidocaine 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 66 97.36 Very High Very High Very High
Eosinophilia 4 92.08 High High
Bronchial Hyperreactivity 2 89.36 High High
Pulmonary Disease 120 87.04 High High
Disease Progression 16 82.80 Quite High
Bronchitis 2 78.24 Quite High
INFLAMMATION 4 75.48 Quite High
Death 20 72.32 Quite High
Emphysema 20 69.76 Quite High
Apoptosis 12 63.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Eotaxin-1 is a CC chemokine (CCL11) that binds to the CC chemokine receptor 3 (CCR3) on the surface of eosinophils thereby inducing eosinophil activation[41] and migration[42].
CCR3 Binding (binds) of Eotaxin-1 in eosinophils associated with chemokine
1) Confidence 0.17 Published 2009 Journal Respir Res Section Body Doc Link PMC2785783 Disease Relevance 1.47 Pain Relevance 0.17
Eotaxin-1 is a CC chemokine (CCL11) that binds to the CC chemokine receptor 3 (CCR3) on the surface of eosinophils thereby inducing eosinophil activation[41] and migration[42].
CCR3 Binding (binds) of CCL11 in eosinophils associated with chemokine
2) Confidence 0.15 Published 2009 Journal Respir Res Section Body Doc Link PMC2785783 Disease Relevance 1.45 Pain Relevance 0.17

General Comments

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