INT288546

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.65
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (THBS1) extracellular region (THBS1) cell adhesion (THBS1)
structural molecule activity (THBS1)
THBS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 42 99.16 Very High Very High Very High
pain pelvic 30 97.56 Very High Very High Very High
Dismenorea 12 56.16 Quite High
Pain 4 52.68 Quite High
Analgesic 2 43.28 Quite Low
visual analogue scale 2 29.52 Quite Low
Disease Link Frequency Relevance Heat
Disease 4 99.24 Very High Very High Very High
Endometriosis 64 99.16 Very High Very High Very High
Reprotox - General 3 32 97.56 Very High Very High Very High
Endometriosis (extended) 2 75.52 Quite High
Gynecological Disease 2 58.76 Quite High
Reprotox - General 1 12 56.16 Quite High
Obesity 2 55.92 Quite High
Pain 4 52.68 Quite High
Teratoma 4 5.00 Very Low Very Low Very Low
Cyst 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that although thrombospondin-1 seems to play a key role in the local development of endometriotic lesions, the disease is not associated with a significant modulation in the levels of circulating thrombospondin-1 and the activity of endometriosis can not be monitored using serum levels.
Regulation (modulation) of Positive_regulation (circulating) of thrombospondin-1 associated with endometriosis and disease
1) Confidence 0.36 Published 2009 Journal J Ovarian Res Section Body Doc Link PMC2785805 Disease Relevance 1.18 Pain Relevance 0.40
Angiogenesis is under the control of numerous inducers, including the vascular endothelial growth factor (VEGF) family and inhibitors, such as thrombospondin-1 (TSP-1) [9]
Regulation (control) of Positive_regulation (inducers) of TSP-1
2) Confidence 0.36 Published 2009 Journal J Ovarian Res Section Body Doc Link PMC2785805 Disease Relevance 1.48 Pain Relevance 0.86

General Comments

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