INT288643

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Coq10a) cellular_component (Coq10a) biological_process (Coq10a)
Coq10a (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 2 26.92 Quite Low
cerebral cortex 3 18.04 Low Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Substantia nigra 4 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
projection neuron 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 2 97.60 Very High Very High Very High
Parkinson's Disease 13 94.92 High High
Neurodegenerative Disease 24 93.72 High High
Congenital Anomalies 1 87.24 High High
Stress 7 74.64 Quite High
Mitochondrial Encephalomyopathies 1 53.40 Quite High
Ataxia 19 47.12 Quite Low
Motor Neuron Diseases 13 46.08 Quite Low
Infantile Spasms 1 45.28 Quite Low
Muscle Hypotonia 1 44.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Induced CoQ10 deficiency in cells genetically altered to lack autophagy resulted in apoptosis, indicating that the autophagy was likely protective.25

Mitochondrial dysfunction and neurodegenerative disease: A rationale for testing CoQ10

Positive_regulation (Induced) of Negative_regulation (deficiency) of CoQ10 associated with parkinson's disease, neurodegenerative disease and apoptosis
1) Confidence 0.39 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2785862 Disease Relevance 0.76 Pain Relevance 0

General Comments

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