INT288731

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 1.25
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Got1, Gpt) cytoplasm (Got1, Gpt) cytosol (Got1)
cellular_component (Gpt) biological_process (Gpt) cellular amino acid metabolic process (Got1)
Got1 (Rattus norvegicus)
Gpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 30 100.00 Very High Very High Very High
Paracetamol 115 99.66 Very High Very High Very High
ketamine 5 81.48 Quite High
Inflammation 15 5.00 Very Low Very Low Very Low
alcohol 10 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 55 93.92 High High
Body Weight 35 84.64 Quite High
Injury 95 79.72 Quite High
Stress 25 5.00 Very Low Very Low Very Low
Poisoning 15 5.00 Very Low Very Low Very Low
Fatty Liver 15 5.00 Very Low Very Low Very Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low
Necrosis 10 5.00 Very Low Very Low Very Low
Protein Deficiency 10 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glutamate-pyruvate transaminase (GPT) and glutamate-oxaloacetate transaminase (GOT) were measured with the Sigma transaminase [ALT/GPT and AST/GOT] Diagnostic kit.
glutamate-oxaloacetate transaminase Binding (measured) of GPT associated with glutamate
1) Confidence 0.23 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2788177 Disease Relevance 0.16 Pain Relevance 0.28
Glutamate-pyruvate transaminase (GPT) and glutamate-oxaloacetate transaminase (GOT) were measured with the Sigma transaminase [ALT/GPT and AST/GOT] Diagnostic kit.
GOT Binding (measured) of GPT associated with glutamate
2) Confidence 0.23 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2788177 Disease Relevance 0.16 Pain Relevance 0.28
Glutamate-pyruvate transaminase (GPT) and glutamate-oxaloacetate transaminase (GOT) were measured with the Sigma transaminase [ALT/GPT and AST/GOT] Diagnostic kit.
GOT Binding (measured) of GPT associated with glutamate
3) Confidence 0.20 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2788177 Disease Relevance 0.16 Pain Relevance 0.28
Whereas GSH level was significantly lower in only group fed 15% corn oil with 6 g/100 g protein among acetaminophen-treated groups, activities of GPT and GOT were significantly elevated in all groups except the one fed beef tallow with 20 g/100 g protein, suggesting low protein might exacerbate drug-induced hepatotoxicity.
GOT Neg (except) Binding (activities) of GPT associated with paracetamol and hepatotoxicity
4) Confidence 0.19 Published 2009 Journal Nutrition Research and Practice Section Abstract Doc Link PMC2788177 Disease Relevance 0.61 Pain Relevance 0.49
Glutamate-pyruvate transaminase (GPT) and glutamate-oxaloacetate transaminase (GOT) were measured with the Sigma transaminase [ALT/GPT and AST/GOT] Diagnostic kit.
GOT Binding (measured) of Glutamate-pyruvate transaminase associated with glutamate
5) Confidence 0.17 Published 2009 Journal Nutrition Research and Practice Section Body Doc Link PMC2788177 Disease Relevance 0.16 Pain Relevance 0.29

General Comments

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