INT288853

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.52
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HSD11B1, LDLR) transport (LDLR) oxidoreductase activity (HSD11B1)
endoplasmic reticulum (HSD11B1) plasma membrane (LDLR) lipid metabolic process (LDLR)
Anatomy Link Frequency
plasma 1
HSD11B1 (Homo sapiens)
LDLR (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 76.96 Quite High
Bile 12 42.56 Quite Low
cINOD 8 5.00 Very Low Very Low Very Low
aspirin 6 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 46 100.00 Very High Very High Very High
Metabolic Syndrome 4 97.00 Very High Very High Very High
Diabetes Mellitus 10 95.64 Very High Very High Very High
Increased Venous Pressure Under Development 84 93.48 High High
Hypertriglyceridemia 8 87.84 High High
Hyperlipidemia 6 86.20 High High
Dyslipidemia /

Combined Dyslipidemia

14 75.00 Quite High
Hypertension 4 30.12 Quite Low
Atherosclerosis 8 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Niacin/laropiprant may also be a treatment option in patients who are at goal with LDL-cholesterol but have abnormal HDL-cholesterol and triglyceride concentrations (Figure 1).
HDL Binding (goal) of LDL-cholesterol associated with disorder of lipid metabolism
1) Confidence 0.26 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2788595 Disease Relevance 0.95 Pain Relevance 0
Niacin (nicotinic acid) is an effective drug which increases the plasma concentration of high-density lipoprotein (HDL)-cholesterol and decreases the concentration of low-density lipoprotein (LDL)-cholesterol, triglycerides and lipoprotein(a).
HDL Binding (concentration) of low-density lipoprotein in plasma associated with disorder of lipid metabolism
2) Confidence 0.26 Published 2009 Journal Vascular Health and Risk Management Section Abstract Doc Link PMC2788595 Disease Relevance 0.49 Pain Relevance 0.04

General Comments

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