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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Apoa1) small molecule metabolic process (HSD11B1) endoplasmic reticulum (HSD11B1)
enzyme binding (Apoa1) lipid binding (Apoa1) extracellular space (Apoa1)
Anatomy Link Frequency
hepatocytes 2
Apoa1 (Rattus norvegicus)
HSD11B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 5 74.48 Quite High
imagery 2 29.36 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 40 100.00 Very High Very High Very High
Rupture 1 92.64 High High
Acute Coronary Syndrome 8 88.72 High High
INFLAMMATION 4 74.48 Quite High
Dyslipidemia /

Combined Dyslipidemia

16 50.00 Quite Low
Hepatocellular Cancer 1 44.08 Quite Low
Adverse Drug Reaction 30 5.00 Very Low Very Low Very Low
Coronary Artery Disease 18 5.00 Very Low Very Low Very Low
Metabolic Syndrome 17 5.00 Very Low Very Low Very Low
Diabetes Mellitus 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pitavastatin was also found to promote ATP-binding cassette transporter A1 (ABCA1) expression in HepG2 cells, and to possibly facilitate HDL neogenesis by ApoA1-dependent cholesterol efflux in hepatocytes.16

Pleiotropic effects of pitavastatin

ApoA1 Spec (possibly) Positive_regulation (facilitate) of Gene_expression (neogenesis) of HDL in hepatocytes associated with disorder of lipid metabolism
1) Confidence 0.03 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2788597 Disease Relevance 0.53 Pain Relevance 0.04

General Comments

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