INT289048

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Context Info
Confidence 0.75
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc38a1)
Anatomy Link Frequency
neurons 1
brainstem 1
Slc38a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 12 98.96 Very High Very High Very High
Neurotransmitter 24 94.08 High High
Glutamate 66 93.36 High High
gABA 12 92.80 High High
addiction 9 5.00 Very Low Very Low Very Low
Glutamate receptor 9 5.00 Very Low Very Low Very Low
excitatory amino acid 6 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 6 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Starvation 3 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The SLC38A1 transporter protein (SAT1) is expressed mainly in neurons (Varoqui et al., 2000; Wang et al., 2000; Chaudhry et al., 2002b; Mackenzie et al., 2003; Melone et al., 2004; Buntup et al., 2008) whereas the SLC38A2 protein (SAT2) is expressed in many tissues, including neurons and potentially in glia (Reimer et al., 2000; Sugawara et al., 2000a; Yao et al., 2000; Gonzalez-Gonzalez et al., 2005; Melone et al., 2006; Jenstad et al., 2009).
Gene_expression (expressed) of SLC38A1 in neurons
1) Confidence 0.75 Published 2009 Journal Neuroscience Section Body Doc Link PMC2789247 Disease Relevance 0 Pain Relevance 0.03
Glutamine transporter expression in the CNS has been observed for system A isoforms SAT1 (also called SA2, SNAT1, NAT2, GlnT and ATA1: Varoqui et al., 2000; Wang et al., 2000; Chaudhry et al., 2002b; Melone et al., 2004) and SAT2 (also called SA1, SNAT2 and ATA2: Reimer et al., 2000; Sugawara et al., 2000a; Yao et al., 2000; Gonzalez-Gonzalez et al., 2005; Melone et al., 2006; Jenstad et al., 2009); system ASC (ASCT2: Broer et al., 1999; Dolinska et al., 2004; Yamamoto et al., 2004); system B0 (B0AT2: Inoue et al., 1996; Takanaga et al., 2005; Broer et al., 2006); system B0,+ (ATB0,+: Sloan and Mager, 1999); system b0,+ (rBAT/b0,+AT: Bertran et al., 1992; Tate et al., 1992; Wells and Hediger, 1992); system L (LAT1 and LAT2: Kanai et al., 1998; Rossier et al., 1999; Segawa et al., 1999); system N (SN1/SNAT3 and SN2/SNAT5: Chaudhry et al., 1999, 2001; Nakanishi et al., 2001; Boulland et al., 2002, 2003; Cubelos et al., 2005) and system y+L (y+LAT2: Broer et al., 2000).
Gene_expression (expression) of Glutamine transporter
2) Confidence 0.04 Published 2009 Journal Neuroscience Section Body Doc Link PMC2789247 Disease Relevance 0 Pain Relevance 0.06
Functional expression of two system A glutamine transporter isoforms in rat auditory brainstem neurons
Gene_expression (expression) of glutamine transporter in brainstem associated with medulla
3) Confidence 0.04 Published 2009 Journal Neuroscience Section Title Doc Link PMC2789247 Disease Relevance 0 Pain Relevance 0.19

General Comments

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