INT289105

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.02
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (WNT3) extracellular space (WNT3) extracellular region (WNT3)
cell morphogenesis (WNT3) proteinaceous extracellular matrix (WNT3) plasma membrane (WNT3)
WNT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 14 71.92 Quite High
cINOD 8 70.12 Quite High
addiction 6 45.16 Quite Low
imagery 3 42.76 Quite Low
Central nervous system 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 48 99.20 Very High Very High Very High
Mantle-cell Lymphoma 2 95.96 Very High Very High Very High
Hematologic Neoplasms 14 91.20 High High
Multiple Myeloma 6 89.80 High High
Epstein-barr Virus 3 72.40 Quite High
Lymphatic System Cancer 16 71.52 Quite High
INFLAMMATION 4 69.56 Quite High
Chronic Lymphoid Leukemia 230 64.56 Quite High
Malignant Neoplastic Disease 13 64.36 Quite High
Apoptosis 72 62.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MCL tumors and cell lines highly and consistently expressed Wnt3 and Wnt10.
Gene_expression (expressed) of Wnt3 associated with cancer
1) Confidence 0.20 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 1.37 Pain Relevance 0
Treatment with EA reduced Wnt1/LRP6 or Wnt3/LRP6, Dvl, and ?
Gene_expression (/) of Wnt3
2) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789382 Disease Relevance 0.30 Pain Relevance 0.16
-catenin pathway, the TOPflash reporter was activated by Wnt1/LRP6 or Wnt3/LRP6, Dvl and ?
Gene_expression (/) of Wnt3
3) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789382 Disease Relevance 0.18 Pain Relevance 0.20
The expression plasmids encoding Wnt1, Wnt3, LRP6, Dvl, ?
Gene_expression (expression) of Wnt3
4) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789382 Disease Relevance 0.17 Pain Relevance 0

General Comments

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