INT28912

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Context Info
Confidence 0.50
First Reported 1989
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cd2) cell adhesion (Cd2) protein complex (Cd2)
Anatomy Link Frequency
T cells 2
muscle 1
Cd2 (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 3 100.00 Very High Very High Very High
tetrodotoxin 1 90.20 High High
repetitive firing 2 80.00 Quite High
addiction 1 76.16 Quite High
cytokine 42 64.80 Quite High
Inflammation 39 51.44 Quite High
abdominal pain 1 47.56 Quite Low
Calcium channel 12 40.28 Quite Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 54 97.24 Very High Very High Very High
Hypopituitarism 3 78.12 Quite High
Adhesions 4 64.24 Quite High
INFLAMMATION 31 51.44 Quite High
Abdominal Pain 1 47.56 Quite Low
Cancer 2 33.16 Quite Low
Death 20 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 18 5.00 Very Low Very Low Very Low
Colitis 17 5.00 Very Low Very Low Very Low
Mucositis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrophysiological studies revealed that only one or two action potentials were triggered by passing a short depolarizing current across the muscle fibre membrane in 0.25 mM Ca2+ Krebs, but in the presence of Cd2+, a train of action potentials (153 +/- 21 Hz) which lasted for 0.7 +/- 0.2 s was induced.
Positive_regulation (induced) of Cd2 in muscle associated with action potential
1) Confidence 0.50 Published 1989 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 2812033 Disease Relevance 0.21 Pain Relevance 0.31
Lamina propria T cells differ from peripherial blood T cells in the fact that the former are better activated by CD2 and CD28 stimulation and show a high expression of IL-2 and IFN?
Positive_regulation (stimulation) of CD2 in T cells
2) Confidence 0.13 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2045662 Disease Relevance 0.12 Pain Relevance 0.03
Determination of Gal-4 binding to T cells was performed by incubating resting and for 48 h CD3/CD28-stimulated PBT and CD2-stimulated LPT with 5 µg/ml Gal-4, a dose not able to induce T cell apoptosis.
Positive_regulation (stimulated) of CD2 in T cells associated with apoptosis
3) Confidence 0.10 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0.15 Pain Relevance 0.06

General Comments

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