INT289232

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6ra) extracellular region (Il6ra) enzyme binding (Il6ra)
Anatomy Link Frequency
endothelial cells 1
Il6ra (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 66 99.60 Very High Very High Very High
chemokine 2 93.44 High High
cytokine 26 83.08 Quite High
rheumatoid arthritis 2 50.00 Quite Low
metalloproteinase 2 46.40 Quite Low
Inflammatory mediators 4 12.40 Low Low
Arthritis 10 5.00 Very Low Very Low Very Low
abatacept 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 68 99.60 Very High Very High Very High
Disease 30 93.92 High High
Rheumatoid Arthritis 122 89.08 High High
Targeted Disruption 10 77.92 Quite High
Adhesions 2 68.40 Quite High
Granuloma 4 39.28 Quite Low
Mycobacterial Infection 2 36.48 Quite Low
Infection 8 35.20 Quite Low
Pneumonia 2 25.96 Quite Low
Fatigue 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, sIL-6R release from neutrophils as they reach the site of inflammation results in local recruitment of leucocytes through activation of adjacent endothelial cells and subsequent chemokine release [30, 37–39].
Localization (release) of sIL-6R in endothelial cells associated with chemokine and inflammation
1) Confidence 0.06 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2789585 Disease Relevance 0.97 Pain Relevance 0.35
The release of sIL-6R is thought to play a key role in the regulation of acute and chronic inflammation.
Localization (release) of sIL-6R associated with inflammation
2) Confidence 0.06 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2789585 Disease Relevance 1.15 Pain Relevance 0.40

General Comments

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