INT289243

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prtn3) peptidase activity (Prtn3) extracellular space (Il6)
extracellular region (Il6) plasma membrane (Prtn3) enzyme binding (Prtn3)
Il6 (Mus musculus)
Prtn3 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 74.32 Quite High
Inflammation 33 57.00 Quite High
chemokine 1 53.72 Quite High
rheumatoid arthritis 1 50.00 Quite Low
cytokine 13 24.96 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 9 95.36 Very High Very High Very High
Rheumatoid Arthritis 61 94.32 High High
INFLAMMATION 34 57.00 Quite High
Disease 15 35.80 Quite Low
Synovitis 2 28.96 Quite Low
Targeted Disruption 5 19.80 Low Low
Adhesions 1 10.28 Low Low
Fatigue 10 5.00 Very Low Very Low Very Low
Anaemia 9 5.00 Very Low Very Low Very Low
Hypercalcemia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although some studies suggest that IL-6 does not stimulate proteinase production or activity [55, 56], correlations between IL-6 and CRP, as well as CRP and proMMP-3, have been identified in patients with early RA [57].
IL-6 Neg (not) Positive_regulation (stimulate) of proteinase associated with rheumatoid arthritis
1) Confidence 0.00 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2789585 Disease Relevance 0.50 Pain Relevance 0.09

General Comments

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