INT289253

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Stat3) cytoplasm (Stat3) signal transducer activity (Stat3)
cell proliferation (Stat3) extracellular space (Il23a) signal transduction (Stat3)
Anatomy Link Frequency
Th17 cells 1
Il23a (Mus musculus)
Stat3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 13 86.44 High High
Inflammation 33 74.92 Quite High
Inflammatory mediators 2 70.80 Quite High
rheumatoid arthritis 1 50.00 Quite Low
Arthritis 5 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 3 84.28 Quite High
INFLAMMATION 34 74.92 Quite High
Infection 4 56.56 Quite High
Rheumatoid Arthritis 61 50.00 Quite Low
Disease 15 48.24 Quite Low
Pneumonia 1 42.64 Quite Low
Granuloma 2 25.60 Quite Low
Stress 1 24.68 Low Low
Mycobacterial Infection 1 22.96 Low Low
Fatigue 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-23, which also activates STAT3, is important in the maintenance of Th17 cells.
IL-23 Positive_regulation (activates) of STAT3 in Th17 cells
1) Confidence 0.04 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2789585 Disease Relevance 0.37 Pain Relevance 0.12

General Comments

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