INT289255

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, VEGFA) extracellular region (Il6, VEGFA) growth (VEGFA)
proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
fibroblasts 2
Il6 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 33 92.40 High High
Arthritis 5 66.48 Quite High
rheumatoid arthritis 1 50.00 Quite Low
metalloproteinase 1 5.56 Low Low
cytokine 13 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 61 98.44 Very High Very High Very High
Disease 15 95.80 Very High Very High Very High
INFLAMMATION 34 92.40 High High
Arthritis 4 83.08 Quite High
Synovitis 2 68.48 Quite High
Hypercalcemia 6 46.08 Quite Low
Osteoporosis 9 26.60 Quite Low
Fatigue 10 5.00 Very Low Very Low Very Low
Anaemia 9 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6, in the presence of sIL-6R, increased VEGF levels in cultured synovial fibroblasts from RA patients [67].
IL-6 Positive_regulation (increased) of Gene_expression (levels) of VEGF in fibroblasts associated with rheumatoid arthritis
1) Confidence 0.06 Published 2010 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2789585 Disease Relevance 1.30 Pain Relevance 0.15

General Comments

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