INT289270

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd55)
Anatomy Link Frequency
red blood cells 2
Cd55 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 7 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paroxysmal Nocturnal Hemoglobinuria 97 100.00 Very High Very High Very High
Disease 14 90.80 High High
Hemolysis 29 67.68 Quite High
Rare Diseases 1 46.96 Quite Low
Thrombosis 25 14.36 Low Low
Infection 7 5.00 Very Low Very Low Very Low
Fatigue 5 5.00 Very Low Very Low Very Low
Chronic Renal Failure 5 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The absence or reduced expression of CD55 and CD59 on PNH red blood cells leads to their increased sensitivity to complement mediated attack.
Positive_regulation (leads) of Gene_expression (expression) of CD55 in red blood cells associated with paroxysmal nocturnal hemoglobinuria
1) Confidence 0.24 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2789686 Disease Relevance 0.60 Pain Relevance 0

General Comments

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