INT289298

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Atp6ap1) cell death (Atp6ap1) extracellular region (CD59)
plasma membrane (CD59) vacuole (Atp6ap1)
CD59 (Homo sapiens)
Atp6ap1 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 7 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paroxysmal Nocturnal Hemoglobinuria 97 87.04 High High
Hemolysis 29 76.28 Quite High
Disease 14 75.84 Quite High
Rare Diseases 1 32.00 Quite Low
Thrombosis 25 22.96 Low Low
Infection 7 5.00 Very Low Very Low Very Low
Fatigue 5 5.00 Very Low Very Low Very Low
Chronic Renal Failure 5 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD55 increases the removal of C3 convertase, thereby reducing the amount of C3 that is cleaved.14 CD59 inhibits C9 binding to C5b, C6, C7 and C8 which together make up the MAC.
Negative_regulation (reducing) of CD59 Binding (binding) of C7
1) Confidence 0.12 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2789686 Disease Relevance 0.51 Pain Relevance 0

General Comments

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