INT289327

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.09
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Racgap1) transport (Racgap1) intracellular (Racgap1)
embryo development (Racgap1) cytoplasm (Racgap1) signal transduction (Racgap1)
Racgap1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 86 99.12 Very High Very High Very High
Hippocampus 25 98.56 Very High Very High Very High
withdrawal 7 95.56 Very High Very High Very High
Spinal cord 66 90.32 High High
Central nervous system 10 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
cerebral cortex 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 27 99.36 Very High Very High Very High
Cv General 4 Under Development 55 99.12 Very High Very High Very High
Death 29 97.72 Very High Very High Very High
Apoptosis 34 97.68 Very High Very High Very High
Cv Unclassified Under Development 30 76.28 Quite High
Adenovirus Infection 2 56.64 Quite High
Cognitive Disorder 12 50.00 Quite Low
Spinal Cord Injury 33 35.52 Quite Low
Injury 8 5.00 Very Low Very Low Very Low
Stroke 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next examined the effect of Rac GTPase inhibition upon oxidative stress damage in the hippocampal CA1 region following GCI.
Spec (examined) Regulation (effect) of Spec (examined) Negative_regulation (inhibition) of Rac GTPase associated with stress and ischemia
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935374 Disease Relevance 1.20 Pain Relevance 0.43
To evaluate the effects of suppressing Rho and Rac GTPase activity in a condition of inducing more extensive cell death, we utilized the protein kinase inhibitor staurosporine.
Regulation (effects) of Negative_regulation (suppressing) of GTPase associated with death
2) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2789715 Disease Relevance 0.88 Pain Relevance 0.20

General Comments

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