INT289335

Context Info Confidence 0.28 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.33 Pain Relevance 0.21

signal transduction (Fgf2) extracellular space (Fgf2) extracellular region (Fgf2) nucleus (Fgf2) embryo development (Fgf2) cytoplasm (Fgf2)

Anatomy Link Frequency neural 2 Fgf2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Central nervous system 10 100.00 Spinal cord 66 90.20 Hippocampus 8 5.00 withdrawal 7 5.00 imagery 4 5.00 cerebral cortex 1 5.00 cytokine 1 5.00 anesthesia 1 5.00 Inflammatory response 1 5.00 Demyelination 1 5.00

Disease Link Frequency Relevance Heat Necrosis 2 100.00 Cancer 2 100.00 Spinal Cord Injury 33 67.04 Cicatrix 1 59.64 Apoptosis 28 5.00 Death 10 5.00 Injury 5 5.00 Infection 4 5.00 Obesity 2 5.00 Adenovirus Infection 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

bFGF: basic fibroblast growth factor; CA: constitutive active form; CNS: central nervous system; DN: dominant negative form; GFP: green fluorescent protein; JNK: c-jun N-terminal kinase; NSPC: neural stem/progenitor cell; p75NTR: p75 neurotrophin receptor; ssDNA: single stranded DNA; TNF: tumor necrosis factor.

Negative_regulation (necrosis) of bFGF Binding (ssDNA) of in neural associated with necrosis, cancer and central nervous system

1) Confidence 0.28 Published 2009 Journal Mol Brain Section Body Doc Link PMC2789715 Disease Relevance 0.33 Pain Relevance 0.21

General Comments

This test has worked.