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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Trib3) nucleus (Trib3) enzyme binding (Trib3)
kinase activity (Trib3)
Anatomy Link Frequency
epidermis 2
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 5 76.16 Quite High
Spinal cord 66 58.80 Quite High
Inflammatory response 6 57.24 Quite High
ischemia 17 50.00 Quite Low
withdrawal 7 41.12 Quite Low
Pain 1 31.00 Quite Low
Inflammation 13 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 98.18 Very High Very High Very High
Obesity 2 88.96 High High
Hematological Disease 1 86.72 High High
Neuroblastoma 1 84.48 Quite High
Injury 17 60.12 Quite High
INFLAMMATION 20 56.88 Quite High
Cv Unclassified Under Development 5 50.00 Quite Low
Apoptosis 30 46.28 Quite Low
Pain 1 31.00 Quite Low
Cv General 4 Under Development 16 15.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-stimulated SH-SY5Y cell line experiments in vitro, SH-SY5Y cells (5 × 106) were pre-incubated with PI3 kinase inhibitor, LY294002 (30 ?
Positive_regulation (incubated) of Negative_regulation (inhibitor) of kinase in SH-SY5Y
1) Confidence 0.03 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2946287 Disease Relevance 0.20 Pain Relevance 0.03
Conditional knockout of Rac1 in the epidermis resulted in depletion of stem cell population and this effect is dependent on negative regulation of c-Myc activity through p21-activiated kinase 2.
Positive_regulation (dependent) of Negative_regulation (regulation) of kinase in epidermis associated with targeted disruption
2) Confidence 0.02 Published 2009 Journal Mol Brain Section Body Doc Link PMC2789715 Disease Relevance 0.34 Pain Relevance 0.10

General Comments

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