INT289494

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (1190002H23Rik) nucleus (1190002H23Rik) cell cycle (1190002H23Rik)
cytoplasm (1190002H23Rik)
Anatomy Link Frequency
retina 1
optic disc 1
1190002H23Rik (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 6 25.32 Quite Low
anesthesia 12 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
glial activation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 8 99.50 Very High Very High Very High
Optic Disorders 12 99.12 Very High Very High Very High
Ocular Hypertension 206 98.94 Very High Very High Very High
Retina Disease 4 97.20 Very High Very High Very High
Glaucoma 26 97.00 Very High Very High Very High
Ganglion Cysts 22 91.52 High High
Blindness 2 90.92 High High
Injury 24 58.92 Quite High
Optic Nerve Injuries 8 55.84 Quite High
Death 18 49.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our previous studies on OHT-induced retinal degeneration in adult rats [26], together with the present studies, indicate that shortly after IOP elevation, severe pathology develops in the retina, affecting the RGC population.
Regulation (affecting) of RGC in retina associated with ocular hypertension and retina disease
1) Confidence 0.04 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2790482 Disease Relevance 0.81 Pain Relevance 0
Glaucomatous optic neuropathy is a human disease that characteristically affects the RGC population but may also affect other retinal neuronal populations [3], including the inner [4] and outer nuclear layers of the retina [5,6]; it provokes optic disc changes and leads to visual field losses that may progress to complete blindness.
Regulation (affects) of RGC in optic disc associated with blindness, disease and optic disorders
2) Confidence 0.02 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2790482 Disease Relevance 0.83 Pain Relevance 0

General Comments

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