INT289537

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Sirt1) nuclear envelope (Sirt1) histone binding (Sirt1)
intracellular (Lep) enzyme binding (Sirt1) cytoplasm (Sirt1)
Lep (Rattus norvegicus)
Sirt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 5 54.48 Quite High
Stress 1 50.00 Quite Low
Aids-related Complex 22 23.12 Low Low
Body Weight 17 21.52 Low Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low
Weight Gain 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Metabolic Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fasting induced down-regulation of hypothalamic S6K signaling is reversed by leptin as well as by inhibition of Sirt1.
leptin Negative_regulation (inhibition) of Sirt1
1) Confidence 0.20 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2790615 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.

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