INT289624

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DMB) extracellular space (RS1) extracellular region (RS1)
cell adhesion (RS1) plasma membrane (HLA-DMB)
HLA-DMB (Homo sapiens)
RS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 48 57.04 Quite High
spinal inflammation 25 55.84 Quite High
rheumatoid arthritis 50 55.68 Quite High
Crohn's disease 13 5.00 Very Low Very Low Very Low
Arthritis 7 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Infliximab 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 53 94.20 High High
Disease 147 88.08 High High
Thyroid Disease 34 57.36 Quite High
Demyelinating Disease 50 57.04 Quite High
Diabetes Mellitus 34 56.16 Quite High
Low Back Pain 25 55.84 Quite High
Rheumatoid Arthritis 57 55.68 Quite High
Hypertension 6 5.00 Very Low Very Low Very Low
Breast Cancer 6 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance HLA-DM (rs151719), a chaperone binder for nascent MHC molecules, could differentially modulate peptide binding and thus antigen presentation.
HLA-DM Regulation (modulate) of rs151719 Binding (binding) of
1) Confidence 0.03 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2791168 Disease Relevance 0.84 Pain Relevance 0.11

General Comments

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