INT289631

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.17
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (RS1) extracellular region (RS1) cell adhesion (RS1)
RS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 89 97.60 Very High Very High Very High
Arthritis 83 64.20 Quite High
Calcium channel 20 63.04 Quite High
aspirin 38 50.00 Quite Low
Multiple sclerosis 50 38.04 Quite Low
spinal inflammation 26 36.84 Quite Low
Inflammation 17 35.44 Quite Low
Crohn's disease 15 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 33 99.52 Very High Very High Very High
Disease 179 99.04 Very High Very High Very High
Diabetes Mellitus 103 98.48 Very High Very High Very High
Rheumatoid Arthritis 96 97.60 Very High Very High Very High
Autoimmune Disease 64 75.20 Quite High
Increased Venous Pressure Under Development 4 69.24 Quite High
Asthma 130 65.44 Quite High
Juvenile Chronic Polyarthritis 72 64.20 Quite High
Arthritis 6 59.28 Quite High
Cerebral Aneurysm 2 54.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, results showed that the rs192808 was not located in any splicing-related site such as donor site (5' boundary), acceptor site (3' boundary) and branch point.
Neg (not) Localization (located) of rs192808
1) Confidence 0.21 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2954844 Disease Relevance 0.17 Pain Relevance 0.03
However, results showed that the location of rs192808 is not in the transcription factor binding site.
Localization (location) of rs192808
2) Confidence 0.21 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2954844 Disease Relevance 0.08 Pain Relevance 0
CDSN (rs1265048) is also located in the MHC on chromosome 6, but has not been described to alter antigen presentation.
Localization (located) of rs1265048
3) Confidence 0.06 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2791168 Disease Relevance 0.49 Pain Relevance 0
The PROCARDIS Consortium's results showed that two different SNPs, rs2891168 and rs10811661, both in the 9p21 region although rs2891168 belongs to the CAD-associated locus while rs10811661 is localized outside, are associated with CAD and diabetes respectively, and the two susceptibility effects are independent [15].
Localization (localized) of rs10811661 associated with coronary artery disease and diabetes mellitus
4) Confidence 0.06 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2871267 Disease Relevance 1.66 Pain Relevance 0
STAT4: Four SNPs (rs11889341, rs7574865, rs8179673 and rs10181656) located in the third intron of STAT4, which showed the strongest association with North American and Swedish RA cases13; Korean RA cases24 were also selected.
Localization (rs8179673) of rs8179673 associated with rheumatoid arthritis
5) Confidence 0.01 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.77 Pain Relevance 0.39

General Comments

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