INT289703

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tnxa (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 16 13.44 Low Low
ischemia 8 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 8 55.60 Quite High
Cancer 2 31.52 Quite Low
Death 2 23.92 Low Low
Severe Combined Immunodeficiency 74 19.48 Low Low
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, as outlined schematically in Fig. 7, interference with steady state levels of factors of the coagulation cascade, such as occurs in Factor VIII KO mice or upon blockade of Factor Xa or thrombin, also overrules this checkpoint, thereby leading to oversized organs.
Negative_regulation (blockade) of Factor Xa
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2791444 Disease Relevance 0.06 Pain Relevance 0
One approach to dissect the role of these factors was to use the anti-coagulant, Clexane (a low molecular weight heparin derivative) which blocks Factor Xa and, to a lesser degree, thrombin.
Negative_regulation (blocks) of Factor Xa
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2791444 Disease Relevance 0 Pain Relevance 0

General Comments

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