INT289738

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.93
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Sat1) transferase activity, transferring acyl groups (Sat1) cytoplasm (Sat1)
Sat1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 33 94.84 High High
Dismenorea 3 61.60 Quite High
endometriosis 3 60.40 Quite High
fibrosis 3 58.04 Quite High
Kinase C 33 5.00 Very Low Very Low Very Low
adenocard 6 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 89.04 High High
Alopecia 3 82.40 Quite High
Female Infertility 3 81.52 Quite High
Pancreatitis 3 75.44 Quite High
Intestinal Cancer 6 65.36 Quite High
Reprotox - General 1 6 61.60 Quite High
Endometriosis (extended) 18 60.40 Quite High
Fibrosis 3 58.04 Quite High
Cancer 3 54.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Fig. 4B, antagonism of the FP receptor completely abolished the potentiation of SAT1 expression by PGF without altering Butaprost-stimulated expression of SAT1.
Negative_regulation (abolished) of Gene_expression (expression) of SAT1
1) Confidence 0.31 Published 2010 Journal Cell Signal Section Body Doc Link PMC2791881 Disease Relevance 0 Pain Relevance 0.05
As shown in Fig. 4C, ablation of AC3 expression reduced SAT1 mRNA expression in FPEP2 cells treated with the combination of Butaprost and PGF to the level observed following stimulation with Butaprost alone (P < 0.001).
Negative_regulation (reduced) of Gene_expression (expression) of SAT1 mRNA
2) Confidence 0.31 Published 2010 Journal Cell Signal Section Body Doc Link PMC2791881 Disease Relevance 0.24 Pain Relevance 0.13
q cross-talk via AC3, such that siRNA knockdown of the AC3 isoform completely inhibited the potentiation of Butaprost-stimulated SAT1 expression by PGF.
Negative_regulation (inhibited) of Gene_expression (expression) of SAT1
3) Confidence 0.30 Published 2010 Journal Cell Signal Section Body Doc Link PMC2791881 Disease Relevance 0.69 Pain Relevance 0.03

General Comments

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