INT289819

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Clcn3) transport (Clcn3) Golgi apparatus (Clcn3)
plasma membrane (Clcn3) intracellular (Clcn3) transmembrane transport (Clcn3)
Anatomy Link Frequency
cardiac muscles 1
Clcn3 (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 2 60.52 Quite High
fibrosis 14 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
antidepressant 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 4 99.64 Very High Very High Very High
Pressure And Volume Under Development 16 62.96 Quite High
Cystic Fibrosis 14 5.00 Very Low Very Low Very Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Bartter Syndrome 6 5.00 Very Low Very Low Very Low
Hypertension 4 5.00 Very Low Very Low Very Low
Hypocalcemia 4 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Glioma 4 5.00 Very Low Very Low Very Low
Vitelliform Macular Dystrophy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, ClC-3 is mainly located in endosomes, and no changes in VDCCs have been detected in cardiac muscles in mice lacking the ClC-3 gene [68].
Localization (located) of ClC-3 in cardiac muscles
1) Confidence 0.09 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792346 Disease Relevance 0.09 Pain Relevance 0.03
Rather, disruption of the ClC-3 gene leads to morphologic abnormalities, suggesting that ClC-3 is important in maintaining pH and Cl?
Localization (important) of ClC-3 associated with congenital anomalies
2) Confidence 0.09 Published 2005 Journal Cell Mol Life Sci Section Body Doc Link PMC2792346 Disease Relevance 0.16 Pain Relevance 0.03

General Comments

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