INT28983

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Context Info
Confidence 0.22
First Reported 1982
Last Reported 1997
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.26
Pain Relevance 3.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr2b) cytoplasm (Htr2b) signal transducer activity (Htr2b)
Anatomy Link Frequency
trachea 1
Htr2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 11 100.00 Very High Very High Very High
gABA 4 100.00 Very High Very High Very High
analgesia 11 99.84 Very High Very High Very High
opiate 11 99.52 Very High Very High Very High
agonist 7 98.32 Very High Very High Very High
Analgesic 3 94.52 High High
noradrenaline 5 93.28 High High
intrathecal 1 85.28 High High
Morphine 1 84.60 Quite High
Eae 1 84.48 Quite High
Disease Link Frequency Relevance Heat
Hypotension 1 95.48 Very High Very High Very High
Syndrome 2 88.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Differential effects of clonidine, B-HT 933 and B-HT 920 in immature rat pups.
Regulation (effects) of B-HT 920 associated with clonidine
1) Confidence 0.22 Published 1987 Journal Pharmacol. Biochem. Behav. Section Title Doc Link 2819900 Disease Relevance 0.26 Pain Relevance 0.66
While conditioned anti-analgesia had no effect on GABA(A) or 5HT2 + 5HT1 non-opiate analgesias, conditioned anti-analgesia completely blocked GABA(B) and 5HT3 non-opiate analgesias.
Neg (no) Regulation (effect) of 5HT2 associated with gaba, opiate and analgesia
2) Confidence 0.07 Published 1997 Journal Pain Section Abstract Doc Link 9231866 Disease Relevance 0 Pain Relevance 2.61
Remarkably, however, the inhibitory action of B-HT 920 in trachea was only marginally affected even by high concentrations of yohimbine (1 x 10(-6) M).
Regulation (affected) of B-HT 920 in trachea
3) Confidence 0.03 Published 1982 Journal Acta Pharmacol Toxicol (Copenh) Section Abstract Doc Link 7102346 Disease Relevance 0 Pain Relevance 0.69

General Comments

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