INT289903

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.48
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Alms1) cilium (Alms1) molecular_function (Alms1)
lipid metabolic process (Alms1) cytoplasm (Alms1)
Alms1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 93.52 High High
Central nervous system 90 93.08 High High
Enkephalin 5 76.28 Quite High
opioid receptor 1 43.44 Quite Low
imagery 226 5.00 Very Low Very Low Very Low
positron emission tomography 22 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
Morphine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Tumor 26 94.72 High High
Meningitis 2 94.00 High High
Pain 2 93.52 High High
Epilepsy 3 92.88 High High
Dementia 4 92.48 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 19 92.08 High High
Cancer 62 66.20 Quite High
Neurodegenerative Disease 7 29.68 Quite Low
Disease 20 25.84 Quite Low
Adhesions 2 15.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This complex approach is known as molecular packaging strategy, where the peptide unit is part of a bulky molecule, dominated by groups that direct BBB penetration and prevent recognition by peptidases.
Regulation (direct) of Localization (penetration) of BBB
1) Confidence 0.14 Published 2008 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC2792490 Disease Relevance 0 Pain Relevance 0.13
The ability of a substance to penetrate the BBB or be transported across BBB is mainly dependent on its physiochemical properties.
Regulation (dependent) of Localization (transported) of BBB
2) Confidence 0.10 Published 2010 Journal Part Fibre Toxicol Section Body Doc Link PMC2847536 Disease Relevance 0.74 Pain Relevance 0.22
The ability of a substance to penetrate the BBB or be transported across BBB is mainly dependent on its physiochemical properties.
Regulation (dependent) of Localization (penetrate) of BBB
3) Confidence 0.10 Published 2010 Journal Part Fibre Toxicol Section Body Doc Link PMC2847536 Disease Relevance 0.74 Pain Relevance 0.22

General Comments

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