INT289954

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APC, CD28) plasma membrane (APC, CD28) chromosome organization (APC)
cell adhesion (APC) cytoskeleton (APC) nucleus (APC)
Anatomy Link Frequency
CD86 1
APC (Homo sapiens)
CD28 (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 68 88.56 High High
abatacept 2 79.84 Quite High
Inflammation 7 67.76 Quite High
cytokine 26 5.00 Very Low Very Low Very Low
Infliximab 15 5.00 Very Low Very Low Very Low
Etanercept 13 5.00 Very Low Very Low Very Low
Adalimumab 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukocytosis 1 91.88 High High
Psoriasis 76 88.56 High High
INFLAMMATION 6 67.76 Quite High
Adhesions 6 54.28 Quite High
Disease 15 45.08 Quite Low
Mycobacterial Infection 8 5.00 Very Low Very Low Very Low
Demyelinating Disease 5 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-B7 antibodies: B7.1 (CD80) and B7.2 (CD86) are surface ligands APC's which bind to T cell CD28 to provide co stimulatory signals, as well as CTLA4 (CD152) to inhibit further T cell activation.
APC Binding (bind) of cell CD28 in CD86
1) Confidence 0.03 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792605 Disease Relevance 0.38 Pain Relevance 0.28

General Comments

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