INT289956

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (APC, ICAM1) plasma membrane (APC, ICAM1) cytosol (APC)
extracellular space (ICAM1) chromosome organization (APC) cytoskeleton (APC)
Anatomy Link Frequency
endothelial cells 1
APC (Homo sapiens)
ICAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 68 79.40 Quite High
Inflammation 7 79.28 Quite High
cytokine 26 5.00 Very Low Very Low Very Low
Infliximab 15 5.00 Very Low Very Low Very Low
Etanercept 13 5.00 Very Low Very Low Very Low
Adalimumab 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 6 98.48 Very High Very High Very High
Disease 15 89.28 High High
Psoriasis 76 79.40 Quite High
INFLAMMATION 6 79.28 Quite High
Leukocytosis 1 31.04 Quite Low
Mycobacterial Infection 8 5.00 Very Low Very Low Very Low
Demyelinating Disease 5 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It interacts with ICAM-1 on APC's to generate signal 2 and regulates T cell trafficking by interacting with the ICAM-1 molecules on endothelial cells and epithelial keratinocytes.
APC Binding (interacts) of ICAM-1 in endothelial cells
1) Confidence 0.04 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792605 Disease Relevance 0.50 Pain Relevance 0.13

General Comments

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