INT289974

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.59
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL2RB) plasma membrane (IL2RB) protein complex assembly (IL2RB)
Anatomy Link Frequency
T cells 2
IL2RB (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 136 93.96 High High
Potency 1 90.32 High High
tolerance 1 86.40 High High
Paracetamol 3 72.84 Quite High
cytokine 55 10.12 Low Low
Infliximab 30 5.00 Very Low Very Low Very Low
Etanercept 26 5.00 Very Low Very Low Very Low
Adalimumab 16 5.00 Very Low Very Low Very Low
Inflammation 14 5.00 Very Low Very Low Very Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 152 93.96 High High
Disease 50 86.00 High High
Diphtheria 9 78.88 Quite High
Cancer 8 73.48 Quite High
Death 3 72.64 Quite High
Apoptosis 10 71.28 Quite High
Fever 6 69.20 Quite High
Graft Vs Host Disease 4 68.40 Quite High
Lymphatic System Cancer 43 65.68 Quite High
Asthenia 2 46.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This optimized fusion protein toxin binds to a high- or intermediate-affinity receptor.27,28 Intermediate affinity receptors have beta (CD122) and gamma (CD132) subunits and bind IL2 with Kd ?
CD122 Binding (binds) of
1) Confidence 0.11 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004568 Disease Relevance 0.43 Pain Relevance 0.16
High quantities of IL-2 are still capable of activating T cells by cross-linking CD122 and CD132.
CD122 Binding (cross) of in T cells
2) Confidence 0.09 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792605 Disease Relevance 0.58 Pain Relevance 0.12
High quantities of IL-2 are still capable of activating T cells by cross-linking CD122 and CD132.
CD122 Binding (linking) of in T cells
3) Confidence 0.09 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792605 Disease Relevance 0.58 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox