INT289984

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Narf)
Anatomy Link Frequency
eye 1
Narf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 3 45.64 Quite Low
agonist 11 5.00 Very Low Very Low Very Low
Glutamate 8 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Clonidine 4 5.00 Very Low Very Low Very Low
Onset of action 3 5.00 Very Low Very Low Very Low
beta blocker 2 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 90 100.00 Very High Very High Very High
Open-angle Glaucoma 3 98.96 Very High Very High Very High
Glaucoma 80 82.00 Quite High
Low Tension Glaucoma 3 61.68 Quite High
Uveitis 1 49.64 Quite Low
Age-related Macular Degeneration 3 49.20 Quite Low
INFLAMMATION 3 45.64 Quite Low
Conjunctivitis 3 23.56 Low Low
Pigment Disorder 1 15.28 Low Low
Apoptosis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unoprostone decreases IOP by increasing the outflow facility without affecting aqueous humor production.[63] When used in monotherapy, Unoprostone provided a clinically significant IOP-lowering effect, equivalent to that of betaxolol but not to those of timolol and latanoprost.[6465] However, in another study, an aqueous solution of 0.12% unoprostone isopropyl, applied topically to the eye twice daily for six weeks, was as effective as 0.5% timolol in maintaining control of IOP in subjects with chronic open angle glaucoma or ocular hypertension.[66] In a six-month study, it was found that unoprostone isopropyl beneficially provides additive IOP lowering effect to topical ?
Regulation (control) of IOP in eye associated with open-angle glaucoma and ocular hypertension
1) Confidence 0.01 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792620 Disease Relevance 0.78 Pain Relevance 0

General Comments

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