INT290116

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Context Info
Confidence 0.58
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PMEPA1) molecular_function (PMEPA1)
PMEPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 1 99.80 Very High Very High Very High
chemokine 1 95.48 Very High Very High Very High
withdrawal 4 80.08 Quite High
member 8 1 71.80 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Dysautonomia 121 99.84 Very High Very High Very High
Prostate Cancer 45 90.00 High High
Benign Prostatic Hypertrophy 115 89.24 High High
Apoptosis 6 67.48 Quite High
Disease 22 37.72 Quite Low
Hyperplasia 7 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We confirmed that PMEPA1 (Figure 4A), the most dysregulated gene on the microarray, and S100A16 (Figure 4B), were significantly underexpressed in FD samples.
Gene_expression (underexpressed) of PMEPA1 associated with familial dysautonomia
1) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3004942 Disease Relevance 0.66 Pain Relevance 0
TMEPAI (transmembrane prostate androgen-induced protein) was the most highly expressed androgen-regulated gene identified.
Gene_expression (expressed) of TMEPAI
2) Confidence 0.54 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793011 Disease Relevance 0.34 Pain Relevance 0.25

General Comments

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