INT290194

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 7.30
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (PLTP) transport (PLTP) extracellular region (PLTP)
lipid metabolic process (PLTP)
Anatomy Link Frequency
plasma 5
PLTP (Homo sapiens)
Hdl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 14 89.80 High High
Angina 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 308 100.00 Very High Very High Very High
Coronary Artery Disease 105 98.24 Very High Very High Very High
INFLAMMATION 14 89.80 High High
Stress 7 88.72 High High
Atherosclerosis 35 87.12 High High
Targeted Disruption 63 78.40 Quite High
Hypolipidemia 7 63.60 Quite High
Nicotine Addiction 14 46.00 Quite Low
Hypertension 28 45.64 Quite Low
Diabetes Mellitus 35 45.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Plasma PLTP activity is inversely associated with HDL-C levels

Phospholipid transfer protein (PLTP) is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL.

Plasma PLTP Binding (associated) of HDL in Plasma associated with disorder of lipid metabolism
1) Confidence 0.07 Published 2009 Journal Nutr Metab (Lond) Section Title Doc Link PMC2793253 Disease Relevance 0.60 Pain Relevance 0.04
Human plasma PLTP activity was inversely associated with HDL levels and positively related to plasma apoB levels in this Chinese population.
plasma PLTP Binding (associated) of HDL in plasma associated with disorder of lipid metabolism
2) Confidence 0.07 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2793253 Disease Relevance 0.75 Pain Relevance 0
Plasma PLTP activity is inversely associated with HDL-C levels

Phospholipid transfer protein (PLTP) is an important modulator of lipoprotein metabolism, including interparticle phospholipid transfer, remodeling of HDL, cholesterol and phospholipid efflux from peripheral tissues, and the production of hepatic VLDL.

PLTP Binding (associated) of HDL in Plasma associated with disorder of lipid metabolism
3) Confidence 0.06 Published 2009 Journal Nutr Metab (Lond) Section Title Doc Link PMC2793253 Disease Relevance 0.61 Pain Relevance 0.04
PLTP activity contributes to the generation of large HDL as well as small HDL particles [22,23] and may promote catabolism of these particles, thus decreasing HDL levels.
PLTP Binding (generation) of HDL associated with disorder of lipid metabolism
4) Confidence 0.06 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2793253 Disease Relevance 1.90 Pain Relevance 0
The major finding of our study is that PLTP activity inversely associated with plasma HDL-C levels.
PLTP Binding (associated) of HDL in plasma associated with disorder of lipid metabolism
5) Confidence 0.06 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2793253 Disease Relevance 0.94 Pain Relevance 0
We found that human plasma PLTP activity was negatively associated with plasma HDL and apoA-I levels, and positively associated with plasma TG, apoB and apoE levels.
plasma PLTP Binding (associated) of HDL in plasma associated with disorder of lipid metabolism
6) Confidence 0.05 Published 2009 Journal Nutr Metab (Lond) Section Abstract Doc Link PMC2793253 Disease Relevance 0.60 Pain Relevance 0.04
PLTP activity contributes to the generation of large HDL as well as small HDL particles [22,23] and may promote catabolism of these particles, thus decreasing HDL levels.
PLTP Binding (generation) of HDL associated with disorder of lipid metabolism
7) Confidence 0.05 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2793253 Disease Relevance 1.91 Pain Relevance 0

General Comments

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