INT290263

Context Info Confidence 0.62 First Reported 2009 Last Reported 2011 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.23 Pain Relevance 0

cell adhesion (FAT1) plasma membrane (FAT1) nucleus (FAT1) cell-cell signaling (FAT1) cytoplasm (FAT1)

Anatomy Link Frequency muscle cells 1 fat 1 FAT1 (Homo sapiens)

Pain Link Frequency Relevance Heat Catecholamine 14 5.00 tolerance 4 5.00 Restless leg syndrome 1 5.00 addiction 1 5.00 adenocard 1 5.00 Pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Overweight 13 98.96 Facioscapulohumeral Muscular Dystrophy 75 98.94 Diabetes Mellitus 13 98.24 Appetite Loss 7 86.72 Obesity 5 74.64 Sprains And Strains 19 68.00 Body Weight 3 52.40 Disease 21 50.16 Hypersensitivity 1 50.00 Metabolic Syndrome 1 48.04

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In addition to the revealing candidate DNA sequences for FSHD involvement in gene deserts, our data indicate that FAT1 transcription warrants further study of possible differences in FSHD and control muscle cells beyond the few studies involving expression microarrays (11,13).

Transcription (transcription) of FAT1 in muscle cells associated with facioscapulohumeral muscular dystrophy

1) Confidence 0.62 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2794184 Disease Relevance 0.55 Pain Relevance 0

Interestingly, the greatest HIIE-induced fat loss was found in two studies that used overweight type 2 diabetic adults (BMI > 29?

Transcription (found) of fat in fat associated with diabetes mellitus and overweight

2) Confidence 0.07 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.68 Pain Relevance 0

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